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Generation of inducible pluripotent stem cell lines from Alzheimer’s disease patients with APOE e3/e3 genotype

iPSCs were generated from B lymphocytes of two Alzheimer’s disease (AD) patients homozygous for the APOE e3 allele. The iPSCs express pluripotency-specific markers and have the capacity to differentiate into all three embryonic germ layers. Karyotyping analyses confirmed the iPSCs have normal karyot...

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Detalles Bibliográficos
Autores principales: Lee, Jihye, Liu, Zhong, Tusing, Ying Gai, Li, Chao, Westin, Erik, Li, Wei, Zhao, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496340/
https://www.ncbi.nlm.nih.gov/pubmed/34392011
http://dx.doi.org/10.1016/j.scr.2021.102498