Cargando…
Generation of inducible pluripotent stem cell lines from Alzheimer’s disease patients with APOE e3/e3 genotype
iPSCs were generated from B lymphocytes of two Alzheimer’s disease (AD) patients homozygous for the APOE e3 allele. The iPSCs express pluripotency-specific markers and have the capacity to differentiate into all three embryonic germ layers. Karyotyping analyses confirmed the iPSCs have normal karyot...
Autores principales: | Lee, Jihye, Liu, Zhong, Tusing, Ying Gai, Li, Chao, Westin, Erik, Li, Wei, Zhao, Rui |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496340/ https://www.ncbi.nlm.nih.gov/pubmed/34392011 http://dx.doi.org/10.1016/j.scr.2021.102498 |
Ejemplares similares
-
Association of APOE e2 genotype with Alzheimer’s and non-Alzheimer’s neurodegenerative pathologies
por: Goldberg, Terry E., et al.
Publicado: (2020) -
Commentary: Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk
por: Dzianok, Patrycja, et al.
Publicado: (2020) -
Protective effect of the APOE-e3 allele in Alzheimer's disease
por: de-Almada, B.V.P., et al.
Publicado: (2011) -
Vascular hypothesis of Alzheimer’s disease: role of apoE and apoE receptors
por: Bu, Guojun, et al.
Publicado: (2013) -
Should the ApoE genotype be a covariate for clinical trials in Alzheimer disease?
por: Farlow, Martin R
Publicado: (2010)