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Human MAIT cells are devoid of alloreactive potential: prompting their use as universal cells for adoptive immune therapy
BACKGROUND: Mucosal-associated invariant T (MAIT) cells are semi-invariant T cells that recognize microbial antigens presented by the highly conserved MR1 molecule. MAIT cells are predominantly localized in the liver and barrier tissues and are potent effectors of antimicrobial defense. MAIT cells a...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496386/ https://www.ncbi.nlm.nih.gov/pubmed/34615705 http://dx.doi.org/10.1136/jitc-2021-003123 |