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Human MAIT cells are devoid of alloreactive potential: prompting their use as universal cells for adoptive immune therapy

BACKGROUND: Mucosal-associated invariant T (MAIT) cells are semi-invariant T cells that recognize microbial antigens presented by the highly conserved MR1 molecule. MAIT cells are predominantly localized in the liver and barrier tissues and are potent effectors of antimicrobial defense. MAIT cells a...

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Detalles Bibliográficos
Autores principales: Tourret, Marie, Talvard-Balland, Nana, Lambert, Marion, Ben Youssef, Ghada, Chevalier, Mathieu F, Bohineust, Armelle, Yvorra, Thomas, Morin, Florence, Azarnoush, Saba, Lantz, Olivier, Dalle, Jean-Hugues, Caillat-Zucman, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496386/
https://www.ncbi.nlm.nih.gov/pubmed/34615705
http://dx.doi.org/10.1136/jitc-2021-003123