The RNA N6-Methyladenosine Methyltransferase METTL3 Promotes the Progression of Kidney Cancer via N6-Methyladenosine-Dependent Translational Enhancement of ABCD1

The role of N6-methyladenosine (m(6)A)-modifying proteins in cancer progression depends on the cell type and mRNA affected. However, the biological role and underlying mechanism of m(6)A in kidney cancer is limited. Here, we discovered the variability in m(6)A methyltransferase METTL3 expression was...

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Detalles Bibliográficos
Autores principales: Shi, Yue, Dou, Yanliang, Zhang, Jianye, Qi, Jie, Xin, Zijuan, Zhang, Mingxin, Xiao, Yu, Ci, Weimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496489/
https://www.ncbi.nlm.nih.gov/pubmed/34631715
http://dx.doi.org/10.3389/fcell.2021.737498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496489/
https://www.ncbi.nlm.nih.gov/pubmed/34631715
http://dx.doi.org/10.3389/fcell.2021.737498

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