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Loss of Elp1 perturbs histone H2A.Z and the Notch signaling pathway

Elongator dysfunction is increasingly recognized as a contributor to multiple neurodevelopmental and neurodegenerative disorders including familial dysautonomia, intellectual disability, amyotrophic lateral sclerosis, and autism spectrum disorder. Although numerous cellular processes are perturbed i...

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Detalles Bibliográficos
Autores principales: Cameron, BreAnna, Lehrmann, Elin, Chih, Tien, Walters, Joseph, Buksch, Richard, Snyder, Sara, Goffena, Joy, Lefcort, Frances, Becker, Kevin G., George, Lynn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496692/
https://www.ncbi.nlm.nih.gov/pubmed/34590699
http://dx.doi.org/10.1242/bio.058979