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Loss of Elp1 perturbs histone H2A.Z and the Notch signaling pathway
Elongator dysfunction is increasingly recognized as a contributor to multiple neurodevelopmental and neurodegenerative disorders including familial dysautonomia, intellectual disability, amyotrophic lateral sclerosis, and autism spectrum disorder. Although numerous cellular processes are perturbed i...
Autores principales: | Cameron, BreAnna, Lehrmann, Elin, Chih, Tien, Walters, Joseph, Buksch, Richard, Snyder, Sara, Goffena, Joy, Lefcort, Frances, Becker, Kevin G., George, Lynn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496692/ https://www.ncbi.nlm.nih.gov/pubmed/34590699 http://dx.doi.org/10.1242/bio.058979 |
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