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ARL3 and ARL13B GTPases participate in distinct steps of INPP5E targeting to the ciliary membrane

INPP5E, a phosphoinositide 5-phosphatase, localizes on the ciliary membrane via its C-terminal prenyl moiety, and maintains the distinct ciliary phosphoinositide composition. The ARL3 GTPase contributes to the ciliary membrane localization of INPP5E by stimulating the release of PDE6D bound to preny...

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Detalles Bibliográficos
Autores principales: Fujisawa, Sayaka, Qiu, Hantian, Nozaki, Shohei, Chiba, Shuhei, Katoh, Yohei, Nakayama, Kazuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496693/
https://www.ncbi.nlm.nih.gov/pubmed/34447983
http://dx.doi.org/10.1242/bio.058843