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Membrane dynamics and protein targets of lipid droplet microautophagy during ER stress-induced proteostasis in the budding yeast, Saccharomyces cerevisiae

Our previous studies reveal a mechanism for lipid droplet (LD)-mediated proteostasis in the endoplasmic reticulum (ER) whereby unfolded proteins that accumulate in the ER in response to lipid imbalance-induced ER stress are removed by LDs and degraded by microlipophagy (µLP), autophagosome-independe...

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Detalles Bibliográficos
Autores principales: Garcia, Enrique J., Liao, Pin-Chao, Tan, Gary, Vevea, Jason D., Sing, Cierra N., Tsang, Catherine A., McCaffery, J. Michael, Boldogh, Istvan R., Pon, Liza A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496710/
https://www.ncbi.nlm.nih.gov/pubmed/33021864
http://dx.doi.org/10.1080/15548627.2020.1826691