Identification of the organic anion transporting polypeptides responsible for the hepatic uptake of the major metabolite of epyrifenacil, S‐3100‐CA, in mice

Epyrifenacil is a novel herbicide that acts as an inhibitor of protoporphyrinogen oxidase (PPO) and produces hepatotoxicity in rodents by inhibiting PPO. Our previous research revealed that the causal substance of hepatotoxicity is S‐3100‐CA, a major metabolite of epyrifenacil, and that human hepato...

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Detalles Bibliográficos
Autores principales: Sakurai, Kengo, Kuroda, Tomohiro, Abe, Jun, Toda, Hiroshi, Kitamoto, Sachiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496750/
https://www.ncbi.nlm.nih.gov/pubmed/34619012
http://dx.doi.org/10.1002/prp2.877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496750/
https://www.ncbi.nlm.nih.gov/pubmed/34619012
http://dx.doi.org/10.1002/prp2.877

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