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Identification of the organic anion transporting polypeptides responsible for the hepatic uptake of the major metabolite of epyrifenacil, S‐3100‐CA, in mice
Epyrifenacil is a novel herbicide that acts as an inhibitor of protoporphyrinogen oxidase (PPO) and produces hepatotoxicity in rodents by inhibiting PPO. Our previous research revealed that the causal substance of hepatotoxicity is S‐3100‐CA, a major metabolite of epyrifenacil, and that human hepato...
Autores principales: | Sakurai, Kengo, Kuroda, Tomohiro, Abe, Jun, Toda, Hiroshi, Kitamoto, Sachiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496750/ https://www.ncbi.nlm.nih.gov/pubmed/34619012 http://dx.doi.org/10.1002/prp2.877 |
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