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Influenza A virus segments five and six can harbor artificial introns allowing expanded coding capacity

Influenza A viruses encode their genomes across eight, negative sense RNA segments. The six largest segments produce mRNA transcripts that do not generally splice; however, the two smallest segments are actively spliced to produce the essential viral proteins NEP and M2. Thus, viral utilization of R...

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Detalles Bibliográficos
Autores principales: Froggatt, Heather M., Burke, Kaitlyn N., Chaparian, Ryan R., Miranda, Hector A., Zhu, Xinyu, Chambers, Benjamin S., Heaton, Nicholas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496794/
https://www.ncbi.nlm.nih.gov/pubmed/34570829
http://dx.doi.org/10.1371/journal.ppat.1009951