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4-Coumaroyl-CoA ligases in the biosynthesis of the anti-diabetic metabolite montbretin A

BACKGROUND: Montbretins are rare specialized metabolites found in montbretia (Crocosmia x crocosmiiflora) corms. Montbretin A (MbA) is of particular interest as a novel therapeutic for type-2 diabetes and obesity. There is no scalable production system for this complex acylated flavonol glycoside. M...

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Detalles Bibliográficos
Autores principales: Sunstrum, Frederick G., Liu, Hannah L., Jancsik, Sharon, Madilao, Lufiani L., Bohlmann, Joerg, Irmisch, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496819/
https://www.ncbi.nlm.nih.gov/pubmed/34618820
http://dx.doi.org/10.1371/journal.pone.0257478