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Experimental and mathematical insights on the interactions between poliovirus and a defective interfering genome

During replication, RNA viruses accumulate genome alterations, such as mutations and deletions. The interactions between individual variants can determine the fitness of the virus population and, thus, the outcome of infection. To investigate the effects of defective interfering genomes (DI) on wild...

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Detalles Bibliográficos
Autores principales: Shirogane, Yuta, Rousseau, Elsa, Voznica, Jakub, Xiao, Yinghong, Su, Weiheng, Catching, Adam, Whitfield, Zachary J., Rouzine, Igor M., Bianco, Simone, Andino, Raul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496841/
https://www.ncbi.nlm.nih.gov/pubmed/34570820
http://dx.doi.org/10.1371/journal.ppat.1009277