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Experimental and mathematical insights on the interactions between poliovirus and a defective interfering genome
During replication, RNA viruses accumulate genome alterations, such as mutations and deletions. The interactions between individual variants can determine the fitness of the virus population and, thus, the outcome of infection. To investigate the effects of defective interfering genomes (DI) on wild...
Autores principales: | Shirogane, Yuta, Rousseau, Elsa, Voznica, Jakub, Xiao, Yinghong, Su, Weiheng, Catching, Adam, Whitfield, Zachary J., Rouzine, Igor M., Bianco, Simone, Andino, Raul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496841/ https://www.ncbi.nlm.nih.gov/pubmed/34570820 http://dx.doi.org/10.1371/journal.ppat.1009277 |
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