Cargando…

Hybrid computational modeling demonstrates the utility of simulating complex cellular networks in type 1 diabetes

Persistent destruction of pancreatic β-cells in type 1 diabetes (T1D) results from multifaceted pancreatic cellular interactions in various phase progressions. Owing to the inherent heterogeneity of coupled nonlinear systems, computational modeling based on T1D etiology help achieve a systematic und...

Descripción completa

Detalles Bibliográficos
Autores principales: Shi, Zhenzhen, Li, Yang, Jaberi-Douraki, Majid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496846/
https://www.ncbi.nlm.nih.gov/pubmed/34570760
http://dx.doi.org/10.1371/journal.pcbi.1009413