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Differential expression profile of gluten-specific T cells identified by single-cell RNA-seq

Gluten-specific CD4(+) T cells drive the pathogenesis of celiac disease and circulating gluten-specific T cells can be identified by staining with HLA-DQ:gluten tetramers. In this first single-cell RNA-seq study of tetramer-sorted T cells from untreated celiac disease patients blood, we found that g...

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Detalles Bibliográficos
Autores principales: Yao, Ying, Wyrozżemski, Łukasz, Lundin, Knut E. A., Sandve, Geir Kjetil, Qiao, Shuo-Wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496852/
https://www.ncbi.nlm.nih.gov/pubmed/34618841
http://dx.doi.org/10.1371/journal.pone.0258029