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Differential expression profile of gluten-specific T cells identified by single-cell RNA-seq
Gluten-specific CD4(+) T cells drive the pathogenesis of celiac disease and circulating gluten-specific T cells can be identified by staining with HLA-DQ:gluten tetramers. In this first single-cell RNA-seq study of tetramer-sorted T cells from untreated celiac disease patients blood, we found that g...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496852/ https://www.ncbi.nlm.nih.gov/pubmed/34618841 http://dx.doi.org/10.1371/journal.pone.0258029 |