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A lipoprotein allosterically activates the CwlD amidase during Clostridioides difficile spore formation

Spore-forming pathogens like Clostridioides difficile depend on germination to initiate infection. During gemination, spores must degrade their cortex layer, which is a thick, protective layer of modified peptidoglycan. Cortex degradation depends on the presence of the spore-specific peptidoglycan m...

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Detalles Bibliográficos
Autores principales: Alves Feliciano, Carolina, Eckenroth, Brian E., Diaz, Oscar R., Doublié, Sylvie, Shen, Aimee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496864/
https://www.ncbi.nlm.nih.gov/pubmed/34570752
http://dx.doi.org/10.1371/journal.pgen.1009791