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A lipoprotein allosterically activates the CwlD amidase during Clostridioides difficile spore formation

Spore-forming pathogens like Clostridioides difficile depend on germination to initiate infection. During gemination, spores must degrade their cortex layer, which is a thick, protective layer of modified peptidoglycan. Cortex degradation depends on the presence of the spore-specific peptidoglycan m...

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Detalles Bibliográficos
Autores principales:	Alves Feliciano, Carolina, Eckenroth, Brian E., Diaz, Oscar R., Doublié, Sylvie, Shen, Aimee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496864/ https://www.ncbi.nlm.nih.gov/pubmed/34570752 http://dx.doi.org/10.1371/journal.pgen.1009791

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