Murine Type III interferons are functionally redundant and correlate with bacterial burden during influenza/bacterial super-infection

BACKGROUND: Type III interferon, or interferon lambda (IFNλ) is a crucial antiviral cytokine induced by influenza infection. While IFNλ is important for anti-viral host defense, published data demonstrate that IFNλ is pathogenic during influenza/bacterial super-infection. It is known that polymorphi...

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Detalles Bibliográficos
Autores principales: Rich, Helen E., Antos, Danielle, McCourt, Collin C., Zheng, Wen Quan, Devito, Louis J., McHugh, Kevin J., Gopal, Radha, Wang, Jieru, Alcorn, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496871/
https://www.ncbi.nlm.nih.gov/pubmed/34618816
http://dx.doi.org/10.1371/journal.pone.0255309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496871/
https://www.ncbi.nlm.nih.gov/pubmed/34618816
http://dx.doi.org/10.1371/journal.pone.0255309

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