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Murine Type III interferons are functionally redundant and correlate with bacterial burden during influenza/bacterial super-infection
BACKGROUND: Type III interferon, or interferon lambda (IFNλ) is a crucial antiviral cytokine induced by influenza infection. While IFNλ is important for anti-viral host defense, published data demonstrate that IFNλ is pathogenic during influenza/bacterial super-infection. It is known that polymorphi...
Autores principales: | Rich, Helen E., Antos, Danielle, McCourt, Collin C., Zheng, Wen Quan, Devito, Louis J., McHugh, Kevin J., Gopal, Radha, Wang, Jieru, Alcorn, John F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496871/ https://www.ncbi.nlm.nih.gov/pubmed/34618816 http://dx.doi.org/10.1371/journal.pone.0255309 |
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