Cargando…

An Application of the Patient Rule-Induction Method to Detect Clinically Meaningful Subgroups from Failed Phase III Clinical Trials

BACKGROUND: Phase III superiority clinical trials have negative results (new treatment is not statistically better than standard of care) due to a number of factors, including patient and disease heterogeneity. However, even a treatment regime that fails to show population-level clinical improvement...

Descripción completa

Detalles Bibliográficos
Autor principal: Dyson, Greg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496893/
https://www.ncbi.nlm.nih.gov/pubmed/34632463
http://dx.doi.org/10.23937/2469-5831/1510038