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Meningeal γδ T cells regulate anxiety-like behavior via IL-17a signaling in neurons

Interleukin-17a (IL-17a) has been highly conserved during evolution of the vertebrate immune system and widely studied in contexts of infection and autoimmunity. Studies suggest that IL-17a promotes behavioral changes in experimental models of autism and aggregation behavior in worms. Here, through...

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Detalles Bibliográficos
Autores principales: de Lima, Kalil Alves, Rustenhoven, Justin, Da Mesquita, Sandro, Wall, Morgan, Salvador, Andrea Francesca, Smirnov, Igor, Martelossi, Guilherme Cebinelli, Mamuladze, Tornike, Baker, Wendy, Papadopoulos, Zach, Lopes, Maria Beatriz, Cao, William Sam, Xie, Xinmin Simon, Herz, Jasmin, Kipnis, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496952/
https://www.ncbi.nlm.nih.gov/pubmed/32929273
http://dx.doi.org/10.1038/s41590-020-0776-4