Inhibition of SARS-CoV-2 polymerase by nucleotide analogs from a single-molecule perspective

The absence of ‘shovel-ready’ anti-coronavirus drugs during vaccine development has exceedingly worsened the SARS-CoV-2 pandemic. Furthermore, new vaccine-resistant variants and coronavirus outbreaks may occur in the near future, and we must be ready to face this possibility. However, efficient anti...

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Detalles Bibliográficos
Autores principales: Seifert, Mona, Bera, Subhas C, van Nies, Pauline, Kirchdoerfer, Robert N, Shannon, Ashleigh, Le, Thi-Tuyet-Nhung, Meng, Xiangzhi, Xia, Hongjie, Wood, James M, Harris, Lawrence D, Papini, Flavia S, Arnold, Jamie J, Almo, Steven, Grove, Tyler L, Shi, Pei-Yong, Xiang, Yan, Canard, Bruno, Depken, Martin, Cameron, Craig E, Dulin, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Microbiology and Infectious Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497053/
https://www.ncbi.nlm.nih.gov/pubmed/34617885
http://dx.doi.org/10.7554/eLife.70968

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497053/
https://www.ncbi.nlm.nih.gov/pubmed/34617885
http://dx.doi.org/10.7554/eLife.70968

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