A modified fluctuation assay reveals a natural mutator phenotype that drives mutation spectrum variation within Saccharomyces cerevisiae

Although studies of Saccharomyces cerevisiae have provided many insights into mutagenesis and DNA repair, most of this work has focused on a few laboratory strains. Much less is known about the phenotypic effects of natural variation within S. cerevisiae’s DNA repair pathways. Here, we use natural p...

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Detalles Bibliográficos
Autores principales: Jiang, Pengyao, Ollodart, Anja R, Sudhesh, Vidha, Herr, Alan J, Dunham, Maitreya J, Harris, Kelley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Evolutionary Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497059/
https://www.ncbi.nlm.nih.gov/pubmed/34523420
http://dx.doi.org/10.7554/eLife.68285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497059/
https://www.ncbi.nlm.nih.gov/pubmed/34523420
http://dx.doi.org/10.7554/eLife.68285

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