Common host variation drives malaria parasite fitness in healthy human red cells

The replication of Plasmodium falciparum parasites within red blood cells (RBCs) causes severe disease in humans, especially in Africa. Deleterious alleles like hemoglobin S are well-known to confer strong resistance to malaria, but the effects of common RBC variation are largely undetermined. Here,...

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Detalles Bibliográficos
Autores principales: Ebel, Emily R, Kuypers, Frans A, Lin, Carrie, Petrov, Dmitri A, Egan, Elizabeth S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Evolutionary Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497061/
https://www.ncbi.nlm.nih.gov/pubmed/34553687
http://dx.doi.org/10.7554/eLife.69808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497061/
https://www.ncbi.nlm.nih.gov/pubmed/34553687
http://dx.doi.org/10.7554/eLife.69808

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