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Common host variation drives malaria parasite fitness in healthy human red cells
The replication of Plasmodium falciparum parasites within red blood cells (RBCs) causes severe disease in humans, especially in Africa. Deleterious alleles like hemoglobin S are well-known to confer strong resistance to malaria, but the effects of common RBC variation are largely undetermined. Here,...
Autores principales: | Ebel, Emily R, Kuypers, Frans A, Lin, Carrie, Petrov, Dmitri A, Egan, Elizabeth S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497061/ https://www.ncbi.nlm.nih.gov/pubmed/34553687 http://dx.doi.org/10.7554/eLife.69808 |
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