Curcumin Ameliorates White Matter Injury after Ischemic Stroke by Inhibiting Microglia/Macrophage Pyroptosis through NF-κB Suppression and NLRP3 Inflammasome Inhibition

NLRP3 inflammasome-mediated pyroptosis is a proinflammatory programmed cell death pathway, which plays a vital role in functional outcomes after stroke. We previously described the beneficial effects of curcumin against stroke-induced neuronal damage through modulating microglial polarization. Howev...

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Detalles Bibliográficos
Autores principales: Ran, Yuanyuan, Su, Wei, Gao, Fuhai, Ding, Zitong, Yang, Shuiqing, Ye, Lin, Chen, Xuechai, Tian, Guiqin, Xi, Jianing, Liu, Zongjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497115/
https://www.ncbi.nlm.nih.gov/pubmed/34630845
http://dx.doi.org/10.1155/2021/1552127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497115/
https://www.ncbi.nlm.nih.gov/pubmed/34630845
http://dx.doi.org/10.1155/2021/1552127

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