M6A methylation of DEGS2, a key ceramide-synthesizing enzyme, is involved in colorectal cancer progression through ceramide synthesis

N6-methyladenosine (m6A) is the most prevalent RNA epigenetic regulator in cancer. However, the understanding of m6A modification on lipid metabolism regulation in colorectal cancer (CRC) is very limited. Here, we observed that human CRCs exhibited increased m6A mRNA methylation mediated by dysregul...

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Detalles Bibliográficos
Autores principales: Guo, Wei, Zhang, Cuiyu, Feng, Panpan, Li, Mingying, Wang, Xia, Xia, Yuan, Chen, Dawei, Li, Jingxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497269/
https://www.ncbi.nlm.nih.gov/pubmed/34363020
http://dx.doi.org/10.1038/s41388-021-01987-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497269/
https://www.ncbi.nlm.nih.gov/pubmed/34363020
http://dx.doi.org/10.1038/s41388-021-01987-z

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