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The role of reciprocal fusions in MLL-r acute leukemia: studying the chromosomal translocation t(6;11)

Leukemia patients bearing t(6;11)(q27;q23) translocations can be divided in two subgroups: those with breakpoints in the major breakpoint cluster region of MLL (introns 9–10; associated mainly with AML M1/4/5), and others with breakpoints in the minor breakpoint cluster region (introns 21–23), assoc...

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Detalles Bibliográficos
Autores principales: Kundu, Arpita, Kowarz, Eric, Marschalek, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497272/
https://www.ncbi.nlm.nih.gov/pubmed/34354240
http://dx.doi.org/10.1038/s41388-021-01983-3