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FBP1 regulates proliferation, metastasis, and chemoresistance by participating in C-MYC/STAT3 signaling axis in ovarian cancer

Fructose-1,6-bisphosphatase (FBP1) is a rate-limiting enzyme in gluconeogenesis and an important tumor suppressor in human malignancies. Here, we aimed to investigate the expression profile of FBP1 in ovarian cancer, the molecular mechanisms that regulate FBP1 expression and to examine how the FBP1...

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Detalles Bibliográficos
Autores principales: Li, Haoran, Qi, Zihao, Niu, Yongdong, Yang, Yufei, Li, Mengjiao, Pang, Yangyang, Liu, Mingming, Cheng, Xi, Xu, Midie, Wang, Ziliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497274/
https://www.ncbi.nlm.nih.gov/pubmed/34363022
http://dx.doi.org/10.1038/s41388-021-01957-5