Therapeutic Assay with the Non-toxic C-Terminal Fragment of Tetanus Toxin (TTC) in Transgenic Murine Models of Prion Disease

The non-toxic C-terminal fragment of the tetanus toxin (TTC) has been described as a neuroprotective molecule since it binds to Trk receptors and activates Trk-dependent signaling, activating neuronal survival pathways and inhibiting apoptosis. Previous in vivo studies have demonstrated the ability...

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Detalles Bibliográficos
Autores principales: Betancor, Marina, Moreno-Martínez, Laura, López-Pérez, Óscar, Otero, Alicia, Hernaiz, Adelaida, Barrio, Tomás, Badiola, Juan José, Osta, Rosario, Bolea, Rosa, Martín-Burriel, Inmaculada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497292/
https://www.ncbi.nlm.nih.gov/pubmed/34283400
http://dx.doi.org/10.1007/s12035-021-02489-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497292/
https://www.ncbi.nlm.nih.gov/pubmed/34283400
http://dx.doi.org/10.1007/s12035-021-02489-5

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