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Therapeutic Assay with the Non-toxic C-Terminal Fragment of Tetanus Toxin (TTC) in Transgenic Murine Models of Prion Disease

The non-toxic C-terminal fragment of the tetanus toxin (TTC) has been described as a neuroprotective molecule since it binds to Trk receptors and activates Trk-dependent signaling, activating neuronal survival pathways and inhibiting apoptosis. Previous in vivo studies have demonstrated the ability...

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Detalles Bibliográficos
Autores principales:	Betancor, Marina, Moreno-Martínez, Laura, López-Pérez, Óscar, Otero, Alicia, Hernaiz, Adelaida, Barrio, Tomás, Badiola, Juan José, Osta, Rosario, Bolea, Rosa, Martín-Burriel, Inmaculada
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497292/ https://www.ncbi.nlm.nih.gov/pubmed/34283400 http://dx.doi.org/10.1007/s12035-021-02489-5

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