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Spared Nerve Injury Causes Sexually Dimorphic Mechanical Allodynia and Differential Gene Expression in Spinal Cords and Dorsal Root Ganglia in Rats

Neuropathic pain is more prevalent in women. However, females are under-represented in animal experiments, and the mechanisms of sex differences remain inadequately understood. We used the spared nerve injury (SNI) model in rats to characterize sex differences in pain behaviour, unbiased RNA-Seq and...

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Detalles Bibliográficos
Autores principales: Ahlström, F.H.G., Mätlik, K., Viisanen, H., Blomqvist, K.J., Liu, X., Lilius, T.O., Sidorova, Y., Kalso, E.A., Rauhala, P.V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497331/
https://www.ncbi.nlm.nih.gov/pubmed/34331199
http://dx.doi.org/10.1007/s12035-021-02447-1