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Spared Nerve Injury Causes Sexually Dimorphic Mechanical Allodynia and Differential Gene Expression in Spinal Cords and Dorsal Root Ganglia in Rats
Neuropathic pain is more prevalent in women. However, females are under-represented in animal experiments, and the mechanisms of sex differences remain inadequately understood. We used the spared nerve injury (SNI) model in rats to characterize sex differences in pain behaviour, unbiased RNA-Seq and...
Autores principales: | Ahlström, F.H.G., Mätlik, K., Viisanen, H., Blomqvist, K.J., Liu, X., Lilius, T.O., Sidorova, Y., Kalso, E.A., Rauhala, P.V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497331/ https://www.ncbi.nlm.nih.gov/pubmed/34331199 http://dx.doi.org/10.1007/s12035-021-02447-1 |
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