Genetic Depletion of Amylin/Calcitonin Receptors Improves Memory and Learning in Transgenic Alzheimer’s Disease Mouse Models

Based upon its interactions with amyloid β peptide (Aβ), the amylin receptor, a class B G protein-coupled receptor (GPCR), is a potential modulator of Alzheimer’s disease (AD) pathogenesis. However, past pharmacological approaches have failed to resolve whether activation or blockade of this recepto...

Descripción completa

Detalles Bibliográficos
Autores principales: Patel, Aarti, Kimura, Ryoichi, Fu, Wen, Soudy, Rania, MacTavish, David, Westaway, David, Yang, Jing, Davey, Rachel A., Zajac, Jeffrey D., Jhamandas, Jack H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497456/
https://www.ncbi.nlm.nih.gov/pubmed/34312771
http://dx.doi.org/10.1007/s12035-021-02490-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497456/
https://www.ncbi.nlm.nih.gov/pubmed/34312771
http://dx.doi.org/10.1007/s12035-021-02490-y

Ejemplares similares