Probing the distinct chemosensitivity of Plasmodium vivax liver stage parasites and demonstration of 8-aminoquinoline radical cure activity in vitro

Improved control of Plasmodium vivax malaria can be achieved with the discovery of new antimalarials with radical cure efficacy, including prevention of relapse caused by hypnozoites residing in the liver of patients. We screened several compound libraries against P. vivax liver stages, including 15...

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Detalles Bibliográficos
Autores principales: Maher, Steven P., Vantaux, Amélie, Chaumeau, Victor, Chua, Adeline C. Y., Cooper, Caitlin A., Andolina, Chiara, Péneau, Julie, Rouillier, Mélanie, Rizopoulos, Zaira, Phal, Sivchheng, Piv, Eakpor, Vong, Chantrea, Phen, Sreyvouch, Chhin, Chansophea, Tat, Baura, Ouk, Sivkeng, Doeurk, Bros, Kim, Saorin, Suriyakan, Sangrawee, Kittiphanakun, Praphan, Awuku, Nana Akua, Conway, Amy J., Jiang, Rays H. Y., Russell, Bruce, Bifani, Pablo, Campo, Brice, Nosten, François, Witkowski, Benoît, Kyle, Dennis E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497498/
https://www.ncbi.nlm.nih.gov/pubmed/34620901
http://dx.doi.org/10.1038/s41598-021-99152-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497498/
https://www.ncbi.nlm.nih.gov/pubmed/34620901
http://dx.doi.org/10.1038/s41598-021-99152-9

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