Polycomb condensates can promote epigenetic marks but are not required for sustained chromatin compaction

Organization of the genome into transcriptionally active euchromatin and silenced heterochromatin is essential for eukaryotic cell function. Phase-separation has been implicated in heterochromatin formation, but it is unclear how phase-separated condensates can contribute to stable repression, parti...

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Detalles Bibliográficos
Autores principales: Eeftens, Jorine M., Kapoor, Manya, Michieletto, Davide, Brangwynne, Clifford P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497513/
https://www.ncbi.nlm.nih.gov/pubmed/34620850
http://dx.doi.org/10.1038/s41467-021-26147-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497513/
https://www.ncbi.nlm.nih.gov/pubmed/34620850
http://dx.doi.org/10.1038/s41467-021-26147-5

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