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Polycomb condensates can promote epigenetic marks but are not required for sustained chromatin compaction
Organization of the genome into transcriptionally active euchromatin and silenced heterochromatin is essential for eukaryotic cell function. Phase-separation has been implicated in heterochromatin formation, but it is unclear how phase-separated condensates can contribute to stable repression, parti...
Autores principales: | Eeftens, Jorine M., Kapoor, Manya, Michieletto, Davide, Brangwynne, Clifford P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497513/ https://www.ncbi.nlm.nih.gov/pubmed/34620850 http://dx.doi.org/10.1038/s41467-021-26147-5 |
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