Theory and simulations of condensin mediated loop extrusion in DNA

Condensation of hundreds of mega-base-pair-long human chromosomes in a small nuclear volume is a spectacular biological phenomenon. This process is driven by the formation of chromosome loops. The ATP consuming motor, condensin, interacts with chromatin segments to actively extrude loops. Motivated...

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Detalles Bibliográficos
Autores principales: Takaki, Ryota, Dey, Atreya, Shi, Guang, Thirumalai, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497514/
https://www.ncbi.nlm.nih.gov/pubmed/34620869
http://dx.doi.org/10.1038/s41467-021-26167-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497514/
https://www.ncbi.nlm.nih.gov/pubmed/34620869
http://dx.doi.org/10.1038/s41467-021-26167-1

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