Haplotyping-based preimplantation genetic testing reveals parent-of-origin specific mechanisms of aneuploidy formation

Chromosome instability is inherent to human IVF embryos, but the full spectrum and developmental fate of chromosome anomalies remain uncharacterized. Using haplotyping-based preimplantation genetic testing for monogenic diseases (PGT-M), we mapped the parental and mechanistic origin of common and ra...

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Detalles Bibliográficos
Autores principales: Tšuiko, Olga, Vanneste, Michiel, Melotte, Cindy, Ding, Jia, Debrock, Sophie, Masset, Heleen, Peters, Maire, Salumets, Andres, De Leener, Anne, Pirard, Céline, Kluyskens, Candice, Hostens, Katleen, van de Vijver, Arne, Peeraer, Karen, Denayer, Ellen, Vermeesch, Joris Robert, Dimitriadou, Eftychia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497526/
https://www.ncbi.nlm.nih.gov/pubmed/34620870
http://dx.doi.org/10.1038/s41525-021-00246-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497526/
https://www.ncbi.nlm.nih.gov/pubmed/34620870
http://dx.doi.org/10.1038/s41525-021-00246-0

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