Sulforaphane downregulated fatty acid synthase and inhibited microtubule-mediated mitophagy leading to apoptosis

We previously demonstrated that sulforaphane (SFN) inhibited autophagy leading to apoptosis in human non-small cell lung cancer (NSCLC) cells, but the underlying subcellular mechanisms were unknown. Hereby, high-performance liquid chromatography-tandem mass spectrometry uncovered that SFN regulated...

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Detalles Bibliográficos
Autores principales: Yan, Yuting, Zhou, Yan, Li, Juntao, Zheng, Zhongnan, Hu, Yabin, Li, Lei, Wu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497537/
https://www.ncbi.nlm.nih.gov/pubmed/34620841
http://dx.doi.org/10.1038/s41419-021-04198-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497537/
https://www.ncbi.nlm.nih.gov/pubmed/34620841
http://dx.doi.org/10.1038/s41419-021-04198-2

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