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GnRHa protects the ovarian reserve by reducing endoplasmic reticulum stress during cyclophosphamide-based chemotherapy

Chemotherapy-induced ovarian dysfunction is a serious adverse effect in premenopausal patients with cancer. Gonadotrophin-releasing hormone analogs (GnRHa) protect ovarian function, but its molecular mechanisms have not yet been determined. In this study, we attempted to determine the previously unk...

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Detalles Bibliográficos
Autores principales: Li, Xiaolin, Liu, Sixuan, Chen, Xuan, Huang, Run, Ma, Lisi, Weng, Huaiyu, Yu, Yang, Zong, Xiangyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497541/
https://www.ncbi.nlm.nih.gov/pubmed/34620881
http://dx.doi.org/10.1038/s41523-021-00340-7