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DHHC9-mediated GLUT1 S-palmitoylation promotes glioblastoma glycolysis and tumorigenesis

Glucose transporter GLUT1 is a transmembrane protein responsible for the uptake of glucose into the cells of many tissues through facilitative diffusion. Plasma membrane (PM) localization is essential for glucose uptake by GLUT1. However, the mechanism underlying GLUT1 PM localization remains enigma...

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Detalles Bibliográficos
Autores principales: Zhang, Zhenxing, Li, Xin, Yang, Fan, Chen, Chao, Liu, Ping, Ren, Yi, Sun, Pengkai, Wang, Zixiong, You, Yongping, Zeng, Yi-Xin, Li, Xinjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497546/
https://www.ncbi.nlm.nih.gov/pubmed/34620861
http://dx.doi.org/10.1038/s41467-021-26180-4