Pharmacological inhibition of Mint3 attenuates tumour growth, metastasis, and endotoxic shock

Hypoxia-inducible factor-1 (HIF-1) plays essential roles in human diseases, though its central role in oxygen homoeostasis hinders the development of direct HIF-1-targeted pharmacological approaches. Here, we surveyed small-molecule compounds that efficiently inhibit the transcriptional activity of...

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Detalles Bibliográficos
Autores principales: Sakamoto, Takeharu, Fukui, Yuya, Kondoh, Yasumitsu, Honda, Kaori, Shimizu, Takeshi, Hara, Toshiro, Hayashi, Tetsuro, Saitoh, Yurika, Murakami, Yoshinori, Inoue, Jun-ichiro, Kaneko, Shuichi, Osada, Hiroyuki, Seiki, Motoharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497560/
https://www.ncbi.nlm.nih.gov/pubmed/34621018
http://dx.doi.org/10.1038/s42003-021-02701-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497560/
https://www.ncbi.nlm.nih.gov/pubmed/34621018
http://dx.doi.org/10.1038/s42003-021-02701-1

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