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RN7SK small nuclear RNA controls bidirectional transcription of highly expressed gene pairs in skin

Pausing of RNA polymerase II (Pol II) close to promoters is a common regulatory step in RNA synthesis, and is coordinated by a ribonucleoprotein complex scaffolded by the noncoding RNA RN7SK. The function of RN7SK-regulated gene transcription in adult tissue homoeostasis is currently unknown. Here,...

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Detalles Bibliográficos
Autores principales: Bandiera, Roberto, Wagner, Rebecca E., Britto-Borges, Thiago, Dieterich, Christoph, Dietmann, Sabine, Bornelöv, Susanne, Frye, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497571/
https://www.ncbi.nlm.nih.gov/pubmed/34620876
http://dx.doi.org/10.1038/s41467-021-26083-4