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How Does Mucorales Benefit from the Dysregulated Iron Homeostasis During SARS-CoV-2 Infection?

Mucorales is the cause of mucormycosis, an emerging opportunistic infection in the era of coronavirus disease 2019 (COVID-19) pandemic. Condition of hyperglycemia, diabetes mellitus, and acidosis; dysregulated iron homeostasis in the form of hyperferritinemic syndrome, and high concentration of iron...

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Detalles Bibliográficos
Autores principales: Lugito, Nata Pratama Hardjo, Cucunawangsih, Cucunawangsih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497685/
https://www.ncbi.nlm.nih.gov/pubmed/34623597
http://dx.doi.org/10.1007/s11046-021-00594-6
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author Lugito, Nata Pratama Hardjo
Cucunawangsih, Cucunawangsih
author_facet Lugito, Nata Pratama Hardjo
Cucunawangsih, Cucunawangsih
author_sort Lugito, Nata Pratama Hardjo
collection PubMed
description Mucorales is the cause of mucormycosis, an emerging opportunistic infection in the era of coronavirus disease 2019 (COVID-19) pandemic. Condition of hyperglycemia, diabetes mellitus, and acidosis; dysregulated iron homeostasis in the form of hyperferritinemic syndrome, and high concentration of iron in circulation; and endothelial injury related to abundance glucose regulated protein 78 (GRP78), which are present in severe COVID-19, could favor Mucorales infection. In this short communication, we summarized how the dysregulated iron homeostasis in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection benefits Mucorales.
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spelling pubmed-84976852021-10-08 How Does Mucorales Benefit from the Dysregulated Iron Homeostasis During SARS-CoV-2 Infection? Lugito, Nata Pratama Hardjo Cucunawangsih, Cucunawangsih Mycopathologia Short Communication Mucorales is the cause of mucormycosis, an emerging opportunistic infection in the era of coronavirus disease 2019 (COVID-19) pandemic. Condition of hyperglycemia, diabetes mellitus, and acidosis; dysregulated iron homeostasis in the form of hyperferritinemic syndrome, and high concentration of iron in circulation; and endothelial injury related to abundance glucose regulated protein 78 (GRP78), which are present in severe COVID-19, could favor Mucorales infection. In this short communication, we summarized how the dysregulated iron homeostasis in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection benefits Mucorales. Springer Netherlands 2021-10-08 2021 /pmc/articles/PMC8497685/ /pubmed/34623597 http://dx.doi.org/10.1007/s11046-021-00594-6 Text en © The Author(s), under exclusive licence to Springer Nature B.V. 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Short Communication
Lugito, Nata Pratama Hardjo
Cucunawangsih, Cucunawangsih
How Does Mucorales Benefit from the Dysregulated Iron Homeostasis During SARS-CoV-2 Infection?
title How Does Mucorales Benefit from the Dysregulated Iron Homeostasis During SARS-CoV-2 Infection?
title_full How Does Mucorales Benefit from the Dysregulated Iron Homeostasis During SARS-CoV-2 Infection?
title_fullStr How Does Mucorales Benefit from the Dysregulated Iron Homeostasis During SARS-CoV-2 Infection?
title_full_unstemmed How Does Mucorales Benefit from the Dysregulated Iron Homeostasis During SARS-CoV-2 Infection?
title_short How Does Mucorales Benefit from the Dysregulated Iron Homeostasis During SARS-CoV-2 Infection?
title_sort how does mucorales benefit from the dysregulated iron homeostasis during sars-cov-2 infection?
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497685/
https://www.ncbi.nlm.nih.gov/pubmed/34623597
http://dx.doi.org/10.1007/s11046-021-00594-6
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