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How Does Mucorales Benefit from the Dysregulated Iron Homeostasis During SARS-CoV-2 Infection?
Mucorales is the cause of mucormycosis, an emerging opportunistic infection in the era of coronavirus disease 2019 (COVID-19) pandemic. Condition of hyperglycemia, diabetes mellitus, and acidosis; dysregulated iron homeostasis in the form of hyperferritinemic syndrome, and high concentration of iron...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497685/ https://www.ncbi.nlm.nih.gov/pubmed/34623597 http://dx.doi.org/10.1007/s11046-021-00594-6 |
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author | Lugito, Nata Pratama Hardjo Cucunawangsih, Cucunawangsih |
author_facet | Lugito, Nata Pratama Hardjo Cucunawangsih, Cucunawangsih |
author_sort | Lugito, Nata Pratama Hardjo |
collection | PubMed |
description | Mucorales is the cause of mucormycosis, an emerging opportunistic infection in the era of coronavirus disease 2019 (COVID-19) pandemic. Condition of hyperglycemia, diabetes mellitus, and acidosis; dysregulated iron homeostasis in the form of hyperferritinemic syndrome, and high concentration of iron in circulation; and endothelial injury related to abundance glucose regulated protein 78 (GRP78), which are present in severe COVID-19, could favor Mucorales infection. In this short communication, we summarized how the dysregulated iron homeostasis in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection benefits Mucorales. |
format | Online Article Text |
id | pubmed-8497685 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer Netherlands |
record_format | MEDLINE/PubMed |
spelling | pubmed-84976852021-10-08 How Does Mucorales Benefit from the Dysregulated Iron Homeostasis During SARS-CoV-2 Infection? Lugito, Nata Pratama Hardjo Cucunawangsih, Cucunawangsih Mycopathologia Short Communication Mucorales is the cause of mucormycosis, an emerging opportunistic infection in the era of coronavirus disease 2019 (COVID-19) pandemic. Condition of hyperglycemia, diabetes mellitus, and acidosis; dysregulated iron homeostasis in the form of hyperferritinemic syndrome, and high concentration of iron in circulation; and endothelial injury related to abundance glucose regulated protein 78 (GRP78), which are present in severe COVID-19, could favor Mucorales infection. In this short communication, we summarized how the dysregulated iron homeostasis in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection benefits Mucorales. Springer Netherlands 2021-10-08 2021 /pmc/articles/PMC8497685/ /pubmed/34623597 http://dx.doi.org/10.1007/s11046-021-00594-6 Text en © The Author(s), under exclusive licence to Springer Nature B.V. 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Short Communication Lugito, Nata Pratama Hardjo Cucunawangsih, Cucunawangsih How Does Mucorales Benefit from the Dysregulated Iron Homeostasis During SARS-CoV-2 Infection? |
title | How Does Mucorales Benefit from the Dysregulated Iron Homeostasis During SARS-CoV-2 Infection? |
title_full | How Does Mucorales Benefit from the Dysregulated Iron Homeostasis During SARS-CoV-2 Infection? |
title_fullStr | How Does Mucorales Benefit from the Dysregulated Iron Homeostasis During SARS-CoV-2 Infection? |
title_full_unstemmed | How Does Mucorales Benefit from the Dysregulated Iron Homeostasis During SARS-CoV-2 Infection? |
title_short | How Does Mucorales Benefit from the Dysregulated Iron Homeostasis During SARS-CoV-2 Infection? |
title_sort | how does mucorales benefit from the dysregulated iron homeostasis during sars-cov-2 infection? |
topic | Short Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497685/ https://www.ncbi.nlm.nih.gov/pubmed/34623597 http://dx.doi.org/10.1007/s11046-021-00594-6 |
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