A Linkage-specific Sialic Acid Labeling Strategy Reveals Different Site-specific Glycosylation Patterns in SARS-CoV-2 Spike Protein Produced in CHO and HEK Cell Substrates

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus utilizes the extensively glycosylated spike (S) protein protruding from the viral envelope to bind to angiotensin-converting enzyme-related carboxypeptidase (ACE2) as its primary receptor to mediate host-cell entry. Currently, th...

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Detalles Bibliográficos
Autores principales: Wang, Qiong, Wang, Yan, Yang, Shuang, Lin, Changyi, Aliyu, Lateef, Chen, Yiqun, Parsons, Lisa, Tian, Yuan, Jia, Hongpeng, Pekosz, Andrew, Betenbaugh, Michael J., Cipollo, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497748/
https://www.ncbi.nlm.nih.gov/pubmed/34631661
http://dx.doi.org/10.3389/fchem.2021.735558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497748/
https://www.ncbi.nlm.nih.gov/pubmed/34631661
http://dx.doi.org/10.3389/fchem.2021.735558

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