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Glycyrrhetinic Acid Protects α-Naphthylisothiocyanate- Induced Cholestasis Through Regulating Transporters, Inflammation and Apoptosis

Glycyrrhetinic acid (GA), the active metabolic product of Glycyrrhizin (GL) that is the main ingredient of licorice, was reported to protect against α-naphthylisothiocyanate (ANIT)- induced cholestasis. However, its protective mechanism remains unclear. In our work, the cholestatic liver injury in m...

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Detalles Bibliográficos
Autores principales: Yan, Miao, Guo, Lin, Yang, Yan, Zhang, Bikui, Hou, Zhenyan, Gao, Yue, Gu, Hongmei, Gong, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497752/
https://www.ncbi.nlm.nih.gov/pubmed/34630081
http://dx.doi.org/10.3389/fphar.2021.701240