Tbx4 function during hindlimb development reveals a mechanism that explains the origins of proximal limb defects

We dissect genetically a gene regulatory network that involves the transcription factors Tbx4, Pitx1 and Isl1 acting cooperatively to establish the hindlimb bud, and identify key differences in the pathways that initiate formation of the hindlimb and forelimb. Using live image analysis of murine lim...

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Detalles Bibliográficos
Autores principales: Duboc, Veronique, Sulaiman, Fatima A., Feneck, Eleanor, Kucharska, Anna, Bell, Donald, Holder-Espinasse, Muriel, Logan, Malcolm P. O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497778/
https://www.ncbi.nlm.nih.gov/pubmed/34423345
http://dx.doi.org/10.1242/dev.199580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497778/
https://www.ncbi.nlm.nih.gov/pubmed/34423345
http://dx.doi.org/10.1242/dev.199580

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